Overlooking the city, B&B Cosmoneapolitan is located about a 25-minute walk from the lavishly decorated 8th-century Via San Gregorio Armeno Church. There is also a car park.

The bed & breakfast lies just 1.1 km from Chiostro di San Francesco and only a few steps from the ornate 18th-century opera house "San Carlo Theatre". Parthenope University of Naples is just moments from the B&B Cosmoneapolitan, while Piazza Trieste e Trento bus stop is 100 metres away. The nearby landmarks of Naples include the traffic-free square "Piazza del Plebiscito", located 6 minutes' walk away. Toledo underground station is 600 metres from this 4-star hotel, which is also 3.3 km from the 18th-century National Museum of Capodimonte.

Guestrooms offer a balcony, along with a writing table for guests' comfort. Along with a minibar fridge and tea/coffee making equipment, such essentials as an air conditioner are also available. They feature bathrooms with a bidet and a separate toilet as well as a hair dryer and bathrobes.

B&B Cosmoneapolitan serves a buffet breakfast. Gran Caffe Gambrinus, located within easy reach of this property, will spoil you with Campania cuisine.