Situated nearly a 25-minute walk from the Capodimonte Astronomical Observatory, the 4-star B&B I Tre Santi Naples features an archaeological museum. Wi-Fi throughout the property is available.

The Piazza Carlo III is located not far from the bed & breakfast, and such natural sites as the Orto Botanico di Napoli is merely 0.8 km away. The Naples Underground is within 20 minutes' walk of the B&B I Tre Santi, and Capodichino airport is 5 km away. The Underground Naples lies merely 1.9 km away, while Piazza Garibaldi tube station is in the vicinity of the hotel. The property is about 300 metres from Generale Pignatelli bus stop and around 10 minutes on foot from Napoli Piazza Garibaldi train station in Naples.

B&B I Tre Santi offers rooms with a balcony featuring air conditioning, along with a flat-screen TV with satellite channels. Guests will make use of hair dryers and bath sheets in bathrooms equipped with a bidet, a separate toilet, and a shower.

This Naples hotel also offers a gluten-free breakfast. Pasticceria Bellavita is located next to the accommodation and serves Neapolitan dishes, just around the corner from the property.