Located just 1 km from the octagonal Piazza Vanvitelli, the 5-star B&B Serenella Naples is a mere 6 minutes' walk from Acquario di Napoli Aquarium. The bed & breakfast offers public parking nearby.

The art museum "Museo PAN" is not very far away, while Piazza Amedeo train station is fairly close to this Naples hotel. The B&B Serenella Naples provides easy access to the history museum "Museo delle Torture", which is nearly 25 minutes' walk away. Guests might as well enjoy proximity to Villa Pignatelli, situated 0.8 km away. The Vomero district lies approximately 5 minutes away by car, while Vanvitelli tube station is 900 m from the property. Mondragone bus stop is just moments from the hotel.

B&B Serenella offers rooms with a balcony and a dressing room featuring air conditioning, along with a flat-screen TV with satellite channels. They are furnished with sound-proofed windows, and also come with a minibar fridge. Guests will make use of a hair dryer and bath sheets in bathrooms equipped with a bidet, a separate toilet, and a shower.

The dessert restaurant Leopoldo Cafebar is 150 metres from this accommodation.