Located in the Materdei district of Naples around a 25-minute walk from the 13th - century Castel Nuovo Castle, 78 Materdei Bed & Breakfast Naples boasts an archaeological museum. This 3-star hotel also includes parking.

The basilica Catacombs of San Gaudioso Church is a mere 150 metres away, while Piazza Cavour train station is not far from the bed & breakfast. Guests can visit the Church of Santa Maria in Portico, which is nearly 5 minutes' walk away, and the 1st-floor Pio Monte della Misericordia Gallery which is only 1.4 km from the 78 Materdei Bed & Breakfast. The funerary chapel "Museo Cappella Sansevero" is situated a 19-minute stroll from this accommodation. The hotel is just 350 m from Materdei underground station and just moments from Via Sanita 161 bus stop.

Comprising a kitchen and a kitchenette, the rooms at the 78 Materdei Bed & Breakfast Naples are equipped with a flat-screen TV with satellite channels. Guests can also make use of a bidet, a separate toilet, and a shower, as well as comforts such as hairdryers and towels.

Dining options include Sorbillo, which offers Neapolitan cuisine and is located within 15 minutes' walk of the property.