Located 19 minutes' walk from the 13th - century Castel Nuovo Castle, Palazzo Carafa Santangelo Bed & Breakfast Naples offers access to tourist attractions throughout Naples. The bed & breakfast resides in a historic building featuring such decor details as parquet floors.

This 4-star hotel is notable for its prime location a mere 250 metres from the funerary chapel "Museo Cappella Sansevero" and not far from Naples Central train station. The Palazzo is within 5 minutes' walk of Chiesa dei Santi Filippo e Giacomo Church and within 10 minutes' walk of the 1st-floor Pio Monte della Misericordia Gallery. The ancient underground Catacombe di San Gennaro Burial Grounds is 2.6 km away, while Università underground station is a short way from the property. Capolinea Sita bus station is also 10 minutes' stroll from the hotel.

An iron and ironing board, and air conditioning, along with a mini-bar, tea and coffee-making facilities, provide in-room convenience at the Palazzo Naples. There are separate bedrooms and separate bathrooms with a bidet and a separate toilet provided.

Guests can enjoy a delicious continental breakfast served daily. Neapolitan cuisine is offered at Sorbillo, located 250 metres away.