Nestled just 300 m from the 700s Via San Gregorio Armeno Church, Sant'Alfonso Bed And Breakfast Napoli features an archaeological museum among its highlights. There is public parking nearby and Wi-Fi in public areas.

The Piazza San Gaetano is around 5 minutes' walk away, while Piazza Cavour train station is in proximity to the guest house. The Sant'Alfonso Bed And Breakfast Napoli is 350 metres from the octagonal Pio Monte della Misericordia Chapel and 2 km from the public shopping gallery "Galleria Umberto I". The islet fortress "Ovo Castle" is 2.8 km away, while Università underground station is within reach of this 4-star hotel. The property is also 750 m from Foria - Duomo bus stop.

The allergy-free rooms are fitted with climate control, as well as modern facilities like high-speed internet and a flat-screen TV with satellite channels. They are appointed with a writing desk, and also feature coffee/tea making facilities. Bathroom comforts include hair dryers and a shower cap, and such essentials as a bidet, a separate toilet, and a shower.

Sorbillo, located within a few blocks of Sant'Alfonso Bed And Breakfast Napoli, will spoil you with Neapolitan cuisine.