Boasting an archaeological museum, Casa Sant'Anna Alle Paludi Naples hotel is nestled in the Central district of Naples, approximately a 20-minute walk from the Piazza Cavour.

The Stazione Napoli Centrale is 0.7 km away, while Napoli Piazza Garibaldi train station is fairly close to the guest house. The hotel is also located within 5 minutes' walk of the Porta Nolana and only 600 metres from the Sacred Wheel of the Exposed. The traffic-free square "Piazza del Plebiscito" is 2.4 km away, and Piazza Garibaldi underground station is in the immediate vicinity of the Casa Sant'Anna Alle Paludi. Guests will find Corso Garibaldi bus stop next to this accommodation, about 5 minutes' walk away. Capodichino airport is 5 km away.

The Casa Sant'Anna Alle Paludi Naples offers rooms with a balcony complete with air conditioning. They come equipped with an electric kettle and a fridge. Bathroom facilities include a bidet, a separate toilet, and a shower, as well as comforts such as a dryer and towels.

Da Donato dal 1956 Antica Trattoria e Pizzeria is located a stone's throw from this hotel and serves Italian food.