Featuring a swimming pool, Civico 22 Pisa Hotel is 1.4 km from the Church of San Francesco. A car park is available on site at the guest house.

Situated approximately a 25-minute walk from the Gualandi Tower, this Pisa hotel also gives access to such sports venues as the Arena Garibaldi Stadium, which is around 30 minutes' walk away. The Piccolo Mondo Amusement Park is within 4 km of the Civico 22 and Galileo Galilei airport is 5 km away. Guests can visit historical sights, including the Palazzo della Carovana, located within 35 minutes' walk of the property, and learn more about Pisa. This hotel is within a few blocks of Luzzatto bus station.

The Civico 22 offers rooms with a balcony and a dressing room featuring an iron and an air conditioner, along with a flat-screen TV with satellite channels and a radio. They are appointed with a writing table, and also feature tea/coffee making equipment. Bathrooms include a bidet, a separate toilet, and a shower, along with comforts such as hair dryers and free toiletries. Guests can enjoy views of the garden from this accommodation.

Each morning, the hotel serves a buffet breakfast. Located just 600 m from the Civico 22, the restaurant Bar Amico offers an Italian menu.