Found in the Central district, Diego House Duomo Costa Naples hotel welcomes guests within a 500-metre distance of the Museum of the Treasure of San Gennaro and features an archaeological museum. This guest house comes with Wi-Fi in the rooms.

The 3-star hotel is located a 5-minute walk from the MADRE Museum, a short way from Università tube station. The 17th-century monastery complex "Certosa e Museo di San Martino" is 2.1 km from the Diego House Duomo Costa, while Foria - Duomo bus stop is 750 metres away. This property is a 10-minute drive from the islet fortress "Ovo Castle". The hotel is also in the vicinity of the Piazza Cavour train station.

Comprising a dining area and a kitchen, the rooms at the Diego House Duomo Costa Naples are equipped with a flat-screen TV with satellite channels and pay-per-view channels. Ironing equipment and an air conditioner are featured for guests' comfort. Bathrooms include a bidet, a separate toilet, and a shower, and such comforts as a hairdryer and shower caps.

This accommodation is within 600 metres of the restaurant L'Antica Pizzeria da Michele.