Offering a shopping area and a storage room, Domus Luigi Leone Hotel Naples lies in Chiaia with cool boutiques and designer shops, plus seafood restaurants and elegant bars, merely 1 km from the star-shaped Castel Sant'Elmo and merely 13 minutes' walk from the 17th-century monastery complex "Certosa e Museo di San Martino". Guests can benefit from private car parking available for EUR 30 per day nearby.

The islet fortress "Ovo Castle" is a mere 0.8 km away, while Naples Central train station is 2.6 km from the hotel. You can find the 13th-century Castel Nuovo Castle, which is a great place to explore the area, in proximity to the Domus Luigi Leone Naples. Also, Villa Comunale is situated nearly 5 minutes away by car. The MADRE Museum is 2.4 km away, while Municipio underground station is 750 metres from the hotel. Nicotera bus stop is right around the corner from the Domus Luigi Leone.

The property has 9 rooms, comprising a dressing room and a seating area. A flat-screen TV with satellite channels, along with a mini-fridge-bar and coffee/tea making facilities, are offered. Furnished with a writing desk, they also have soundproof windows. Bathrooms are fitted with a bidet, a separate toilet, and a shower as well as hairdryers and bath sheets.

Gran Caffe Gambrinus is located next to Domus Luigi Leone Hotel and serves Neapolitan dishes, approximately 5 minutes' walk away.