Featuring a barber shop, the deluxe 4-star Domus Sirena Hotel Naples is decorated with tiled floors and offers proximity to Via Caracciolo e Lungomare di Napoli, which is just 7 minutes' stroll away. The recently renovated guest house lies in Chiaia with cool boutiques and designer shops, plus seafood restaurants and elegant bars, 2.4 km from such cultural sights as the public shopping gallery "Galleria Umberto I".

This Naples hotel is located a mere 5 minutes' stroll from Fontana del Leone and nearly a 10-minute ride from Mostra d'Oltremare Convention Center Park. The nearby sports attractions include Arturo Collana Stadium, 2.1 km from the comfortable Domus Sirena Naples. Naples National Archaeological Museum is approximately a 15-minute ride away, and Mergellina underground station is just moments from the accommodation. The hotel is also only 350 metres from Naples Mergellina train station, and 15 minutes' driving distance from Capodichino airport.

Domus Sirena Hotel has 4 rooms, comprising a balcony. A flat-screen TV with satellite channels, along with a minibar, are offered. Air conditioning are featured for guests' comfort. Offering a bidet and a separate toilet, the bathrooms are fitted with hairdryers and towels.

Situated fairly close to the Domus Sirena Naples, the restaurant 50 Kalo Di Ciro Salvo offers a Campania menu.