Duomo61 B&B Naples is a great place to stay in Naples Historical Centre, which is a great choice for travellers interested in churches, old town exploring and museums, a 16-minute walk from the lavish Gesu Nuovo Church. Featuring a luggage room, this hotel is located in proximity to the Souls church "Museo dell'Opera Pia Purgatorio ad Arco".

Guests may find the MADRE Museum within a 200-metre distance of the bed & breakfast, and the Filangieri Civic Museum is about 700 metres away. The Duomo61 B&B stands not far from Museo tube station. This property also gives quick access to the 1st-floor Pio Monte della Misericordia Gallery, which is a 6-minute walk away. Foria - Duomo bus stop is 250 metres from the hotel and within 300 metres of is enough to get to Piazza Cavour train station.

Duomo61 B&B is in the immediate vicinity of the restaurant Di Matteo.