Located a mere 1.8 km from Duomo House Hotel Pisa, guests can reach the old fortress "Fortezza Sangallo". Guests who stay at this Pisa hotel can park their car nearby.

Situated in the vicinity of the Leaning Tower of Pisa, the guest house also gives access to such sports venues as the Arena Garibaldi Stadium, which is just a 13-minute walk away. National Museum of Saint Mathew is merely 1.9 km from the Duomo House Pisa, while Galileo Galilei airport is 5 km from it. The nearby notable religious buildings include the 13th-century Santa Caterina Church, in proximity to the accommodation. Largo San Zeno bus stop, offering a direct link to the city attractions and main places, is within 10 minutes' walk of the hotel.

The rooms at Duomo House Hotel have a sitting area, along with an iron with ironing board for your convenience. A refrigerator and kitchenware are also included.

Situated just near the property, the specialty food market Clorophylla offers a Mediterranean menu.