Located a mere 350 metres from Centro Storico, Murantiche Hotel Naples is within 5 minutes' walk of Via San Gregorio Armeno. Private parking is available nearby as well.

The centre of Naples is a 20 minutes' walk of this guest house. Naples Cathedral is in proximity to the hotel, and MUSA - Museo Universitario delle Scienze e delle Arti is only a 5-minute stroll away. There is Castel Nuovo a 5-minute ride away, and EAV - Capolinea Porta Nolana bus station only 10 minutes' walk from the accommodation. Murantiche Hotel is situated around a 10-minute walk from Universita underground station and relatively near Piazza Cavour train station.

The rooms at this property provide guests with a flat-screen TV with satellite channels, as well as comforts such as ironing facilities and climate control. They come equipped with an electric kettle, an oven, and glassware. Bathroom amenities include a bidet, a separate toilet, and a shower, along with comforts such as hair dryers and shower caps.

The wine bar WineCafe da Mario is situated not very far from this Naples hotel.