Situated around 25 minutes' walk from the Orto Botanico di Napoli, the 4-star Hotel Palazzo Pepe Naples offers a business centre with a range of business amenities. The hotel also provides guests with a safe deposit box and 24-hour security service.

The islet fortress "Ovo Castle" is 2.8 km from this hotel, and the Naples National Archaeological Museum is 2.5 km from it. The Palazzo Pepe Naples stands in the vicinity of Piazza Garibaldi tube station. Explore the historical sights of Naples, starting with the Piazza San Gaetano situated nearly 20 minutes' walk away. The property is located 600 m from Napoli Piazza Garibaldi train station, while Corso Garibaldi bus stop is 400 metres away.

There are 13 rooms at Hotel Palazzo Pepe, each of them has an air conditioner, as well as entertainment amenities such as a flat-screen TV with satellite channels. They are appointed with a writing desk, and also feature a minibar fridge and coffee/tea making machines. A spa bathtub, a walk-in shower, and a separate toilet, along with a hair dryer and bathrobes, are featured.

La Nuova Piazzetta, situated only a 5-minute stroll away, is a perfect place to enjoy Italian cuisine.