Hotel Pignatelli Napoli is a great place to stay in Nordstadt with old maritime buildings, including the Altes Hafenamt museum, and small boats conducting tours, a 14-minute walk from the Naples National Archaeological Museum. Public parking is available nearby as well.

The Museum of the Treasure of San Gennaro is a short way from this guest house, while the upper church "Museo dell'Opera Pia Purgatorio ad Arco" is 650 metres away. The Pignatelli Napoli is located 6 minutes' stroll from the funerary chapel "Museo Cappella Sansevero" and the ornate basilica "Church of San Domenico Maggiore". Nature lovers will appreciate the proximity to Tyrrhenian Sea, which is 0.8 km away. Along with other cultural attractions the 18th-century National Museum of Capodimonte is nestled 5 minutes' drive from this 3-star hotel. The family-run Hotel Pignatelli Napoli is 350 metres from Sanfelice - Bovio bus stop and right near Università underground station.

The rooms at the property are fitted with tile floors and such comforts as air conditioning. Bathrooms, equipped with a separate toilet and a shower, also feature hairdryers and towels.

Guests may find the restaurant Sorbillo an 8-minute walk away.