The comfortable 4-star Naples Plaza Duomo Hotel enjoys a prime location and provides easy access to the Piazza Cavour, a place where guests can shop, located only 1.5 km away. The recently renovated guest house features safety facilities including a safety deposit box and 24-hour security service.

The funerary chapel "Museo Cappella Sansevero" is 950 metres away, and culture-oriented attractions such as the Naples National Archaeological Museum lie nearly a 20-minute stroll from this Naples hotel. Standing just 650 metres from the lavishly decorated 8th-century Via San Gregorio Armeno Church, the Plaza Duomo Naples is 2.2 km from the Piazza dei Martiri. Also, the traffic-free square "Piazza del Plebiscito" lies approximately a 25-minute stroll away, and Università underground station is a short way from the accommodation. The nearest bus stop is Vespucci - Garibaldi, located only 0.7 km away, and Naples Central train station is only 1.3 km away.

The rooms at Naples Plaza Duomo Hotel are allergy-friendly and fitted with complimentary wireless internet and a flat-screen TV with satellite channels as well as a mini-fridge-bar, tea and coffee making facilities. There is also a private bathroom. Bathrooms come with a bidet, a separate toilet, and a shower, along with a hair dryer and towels.

Breakfast is served every morning with cheese, fresh fruits, and fresh pastries. While staying at the Plaza Duomo, guests can choose from dining options nearby, such as L'Antica Pizzeria da Michele, located about a 5-minute ride away, or Cornetteria Mamma Mia at a 5-minute walking distance.