Hotel Villa Serena Castellammare di Stabia gives quick access to Santuario del Sacro Cuore, which is situated approximately 5 minutes' walk away. This 4-star hotel is only 1.3 km from Excavation of Stabiae and provides guests with a solarium and a treatment room.

Cassarmonica Monument is 17 minutes' walk from the hotel, while Via Abbondanza is around 15 minutes away by car. Natural attractions in the area include the Lattari Mountains Regional Park, within a few blocks of the Villa Serena, and a beach is 1.9 km away. This accommodation stands 650 metres from Santuario di Santa Maria della Sanita, popular with pilgrims and tourists alike. The hotel is located 35 km from Capodichino airport and within reach of Viale Europa bus stop.

Hotel Villa Serena has 65 rooms with a balcony. A flat-screen TV with satellite channels along with a mini-fridge-bar are provided. Bathrooms, equipped with a bidet, a separate toilet, and a shower, also feature a hair dryer and bath sheets.

The property has an à la carte restaurant with views of the sea. A lounge bar is available on site. 7 Farine offers a selection of Neapolitan delicacies and lies within 15 minutes' walk of the Villa Serena Castellammare di Stabia.