Located about 20 minutes' walk from Naples Cathedral, Amazonia Hotel Naples is just a 6-minute stroll from Piazza Carlo III.

The guest house is about 5 km from Capodichino airport and a 10-minute drive from such cultural venues as the public shopping gallery "Galleria Umberto I". The area includes such religious sights as Museo Cappella Sansevero (2.1 km) and Gesu Nuovo Church (2.2 km). Also, Catacombe di San Gennaro lies nearly a 10-minute ride away, while Piazza Garibaldi is within close distance of this Naples hotel. The property is located around 10 minutes' walk from Napoli Piazza Garibaldi train station, while Ponte Casanova - Novara bus stop is just 5 minutes' walk away.

The dessert restaurant La Cioccolateria Silva is within easy reach of Amazonia Hotel.